Description | This product is a human neutralizing antibody binding to middle east respiratory syndrome coronavirus (MERS-CoV) Spike glycoprotein. It interacts with the MERS-CoV B domain. It also exhibits high affinity with EBOV glycoprotein and neutralization efficiency against Ebola virus. |
Clonality | Monoclonal |
Host Species | Human |
Target Species | MERS-CoV |
Cross Reactivity | England1, EMC/2012, Jordan-N3/2012 |
Epitope | B domain |
Neutralization Mechanism | It interacts with the MERS-CoV B domain. |
Isotype | IgG |
Expression Species | HEK293F or CHO cell |
Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
Endotoxin | <1 EU/mg |
Form | Liquid |
Purification | Protein A purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
Application | ELISA; BLI; Neut |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Flow Cytometry Protocol |
Target | MERS-CoV S |
Alternative Name | Middle East respiratory syndrome coronavirus spike glycoprotein |
Research Area | Infectious Disease |
Related Disease | Respiratory tract infections, Atypical pneumonia |