Anti-PCSK9 Neutralizing Antibody (V3S-0522-YC2504) (CAT#: V3S-0522-YC2504)

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Datasheet

MSDS

COA

Sub Cat Immunogen Isotype Application Affinity  
V3S-1124-YC2333 His-tagged PCSK9 IgG1 kappa ELISA; Block Inquiry
V3S-0522-YC2505 IgG4 kappa ELISA; Inhib 8.749 pM Inquiry
V3S-0522-YC7528 Human proprotein convertase subtilisin/kexin type 9 IgG WB; Block; FuncS Inquiry
V3S-0522-YC8296 Human proprotein convertase subtilisin/kexin type 9 IgG2 ELISA; WB; Neut Inquiry
V3S-0622-YC2341 IgG2 kappa FuncS Inquiry
V3S-0622-YC421 IgG1 lambda Antagonist; ELISA; FuncS 2.05 nM Inquiry
V3S-0622-YC5177 IgG FuncS Inquiry
V3S-0622-YC5178 IgG WB; FC; IP; ELISA; Neut; FuncS; IF Inquiry
V3S-0622-YC5180 IgG ELISA; FC; IP; FuncS; IF; Neut; ICC Inquiry
V3S-0622-YC5181 IgG Neut; ELISA; IF; IP; FuncS; FC; ICC Inquiry
V3S-0822-YC2191 LDLR binding region of human PCSK9 IgG1 Neut Inquiry
V3S-1022-YC6022 IgG1 kappa IP; IF; FuncS; FC; Neut; ELISA; ICC Inquiry
V3S-1222-YC1103 IgG ELISA; Block Inquiry
V3S-0522-YC7215 IgG ELISA Inquiry
V3S-0522-YC7864 Human proprotein convertase subtilisinkexin type 9 IgG WB; FuncS Inquiry
V3S-0522-YC7866 Human proprotein convertase subtilisinkexin type 9 IgG ELISA; WB Inquiry
V3S-0622-YC2346 IgG ELISA Inquiry
V3S-1022-YC213 IgG ELISA Inquiry
V3S-1022-YC2198 IgG ELISA 8.1 nM Inquiry
V3S-1022-YC31 Human proprotein convertase subtilisin/kexin type 9 (PCSK9) IgG2 kappa Inhib; ELISA 6.3 nM Inquiry
V3S-1022-YC386 IgG1 Inhib Inquiry
V3S-1022-YC526 IgG2 Inhib 0.206 nM Inquiry
V3S-1022-YC753 IgG Inhib Inquiry
V3S-1022-YC81 IgG1 IA Inquiry
V3S-1222-YC1723 IgG ELISA; Inhib Inquiry
V3S-1222-YC1724 IgG ELISA Inquiry
V3S-1222-YC2049 IgG ELISA Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a monoclonal antibody derived from Human (Homo sapiens), which can specifically recognize Proprotein convertase subtilisin/kexin type 9. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Human
Target Species Human
Immunogen His-tagged PCSK9
Isotype IgG1, κ

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application ELISA; Block
Application Notes The antibody is recommended for detection of PCSK9 by ELISA, Block assays.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target PCSK9
Alternative Name Proprotein Convertase Subtilisin/Kexin Type 9; Subtilisin/Kexin-Like Protease PC9; NARC-1; NARC1; PC9; Convertase Subtilisin/Kexin Type 9 Preproprotein; Hypercholesterolemia, Autosomal Dominant 3; Neural Apoptosis Regulated Convertase 1; Neural Apoptosis-Regulated Convertase 1;
Gene ID 255738
UniProt Q8NBP7
Research Area Signal Pathway; Cardiovascular
For research use only, not directly for clinical use.
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