Description | This antibody bound to PfSPZ with high affinity as measured by flow cytometry on live PfSPZ. The PfSPZ-specific monoclonal antibody exhibits potent neutralizing capacity in vitro and in vivo. |
Clonality | Monoclonal |
Host Species | Human |
Target Species | Plasmodium falciparum |
Immunogen | Repeated intravenous injection of irradiated PfSPZ (PfSPZ Vaccine) and then underwent CHMI with live homologous parasites. |
Isotype | IgG |
Expression Species | HEK293F or CHO cell line |
Conjugation | Unconjugated |
Purity | >95% |
Endotoxin | <1 EU/mg |
Form | Liquid |
Purification | Protein A purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
Application | ELISA; WB; FC; Neut |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Flow Cytometry Protocol |
Target | PfSPZ |
Alternative Name | P. falciparum circumsporozoite protein; PfCSP |
UniProt | P02893 |
Research Area | Microbiology |