Anti-Poliovirus Neutralizing Antibody (V3S-0622-YC431) (CAT#: V3S-0622-YC431)

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Datasheet

MSDS

COA

Sub Cat Immunogen Affinity  
V3S-1124-YC1604 All three serotypes of the oral polio vaccine (OPV). 2.8 nM for Poliovirus serotype 1, 2.92 nM for Poliovirus serotype 2, 36.1 nM for Poliovirus serotype 3 Inquiry
V3S-0622-YC432 Poliovirus vaccines Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a human monoclonal antibody that reacts with Poliovirus. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Human
Target Species Poliovirus
Immunogen All three serotypes of the oral polio vaccine (OPV).
Affinity 2.8 nM for Poliovirus serotype 1, 2.92 nM for Poliovirus serotype 2, 36.1 nM for Poliovirus serotype 3
Isotype IgG1

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application ELISA; Neut
Application Notes The antibody is recommended for detection of Poliovirus by ELISA, Neut assays.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target Poliovirus
Alternative Name Poliovirus; polio; poliomyelitis
Research Area Infectious Disease
For research use only, not directly for clinical use.
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