Anti-PvDBP (aa 413-441) Neutralizing Antibody (V3S-0723-FY13) (CAT#: V3S-0723-FY13)

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Datasheet

MSDS

COA

Sub Cat Isotype  
V3S-1124-YC2089 IgG Inquiry
V3S-0723-FY14 IgG1 Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description The mAb is an inhibitory monoclonal antibody that recognizes Plasmodium vivax PvDBP. The antibody reacts with the epitope (aa 413-441) of PvDBP. The mAb identifies a specific inhibitory epitope within SD3 composed of amino acids 413-417 and 425-441. The antibody blocks DBP from binding to erythrocytes. The inhibitory effects of the mAb are not due to disruption of the DBL fold, but rather to the epitope location and disruption of protein function.
Clonality Monoclonal
Host Species Mouse
Target Species Plasmodium vivax
Epitope aa 413-441
Isotype IgG

Property

Expression Species HEK293F or CHO cell line
Conjugation Unconjugated
Purity >95%
Endotoxin <1 EU/mg
Form Liquid
Purification Protein G purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Applications

Application ELISA; Inhib; Block; FuncS

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target PvDBP
Alternative Name Erythrocyte-binding protein; PVDR
Gene ID 5471431
UniProt P22290
For research use only, not directly for clinical use.
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