| Description | Antibody 2D10 is an inhibitory monoclonal antibody that recognizes Plasmodium vivax PvDBP. The antibody 2D10 reacts with the epitope (aa 413-441) of PvDBP. mAb 2D10 identifies a specific inhibitory epitope within SD3 composed of amino acids 413-417 and 425-441. 2D10 blocks DBP from binding to erythrocytes. The inhibitory effects of 2D10 are not due to disruption of the DBL fold, but rather to the epitope location and disruption of protein function. |
| Clonality | Monoclonal |
| Host Species | Mouse |
| Target Species | Plasmodium vivax |
| Epitope | aa 413-441 |
| Isotype | IgG |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein G purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA; Inhib; Block; FuncS |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
