Anti-SIV gp41 Neutralizing Antibody (V3S-0723-FY186) (CAT#: V3S-0723-FY186)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description 4G8 was isolated for its ability to react with the peptide m6687-9 (WQEWERKVDFLEEQITALLEEAQ), corresponding to the mutant sequence behind wild-type SIVmac239 gp41 glycosylation. Antibody 4G8 showed strong binding to peptide m6687 and moderate binding to peptide m6688, but it did not react significantly with any wild-type peptide.
Clonality Monoclonal
Host Species Rhesus macaque
Target Species Simian Immunodeficiency Virus (SIV)
Immunogen SIVmac239-gp41/g23
Epitope WQEWERKVDFLEEQITALLEEAQ
Isotype IgG

Property

Expression Species HEK293F or CHO cell line
Conjugation Unconjugated
Purity >95%
Endotoxin <1 EU/mg
Form Liquid
Purification Protein A purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Applications

Application ELISA; WB; Neut

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target SIV gp41
Alternative Name Simian immunodeficiency virus; SIV
Research Area Microbiology
For research use only, not directly for clinical use.
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