| Description | This product is a human monoclonal antibody that reacts with TCIRG1. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation. Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Epitope | Located in DLPDASVNGWSSDE. |
| Affinity | 1 nM |
| Isotype | IgG kappa |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and/or SEC-HPLC |
| Endotoxin | <1 EU/mg, determined by LAL method |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C. |
| Application | ELISA; RIA; IP; IF; WB |
| Application Notes | The antibody is recommended for detection of TCIRG1 by ELISA, RIA, IP, IF, WB assays. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | TCIRG1 |
| Alternative Name | T Cell Immune Regulator 1, ATPase H+ Transporting V0 Subunit A3; T-Cell, Immune Regulator 1, ATPase, H+ Transporting, Lysosomal V0 Subunit A3; T-Cell Immune Regulator 1, ATPase H+ Transporting V0 Subunit A3; Osteoclastic Proton Pump 116 KDa Subunit; T-Cell Immune Response CDNA 7; ATP6V0A3; ATP6N1C; OC116; TIRC7; T-Cell, Immune Regulator 1, ATPase, H+ Transporting, Lysosomal V0 Protein A Isoform 3; T-Cell, Immune Regulator 1, ATPase, H+ Transporting, Lysosomal V0 Protein A; Vacuolar Proton Translocating ATPase 116 KDa Subunit A Isoform 3; Vacuolar Proton Translocating ATPase 116 KDa Subunit A; V-Type Proton ATPase 116 KDa Subunit A Isoform 3; Specific 116-KDa Vacuolar Proton Pump Subunit; Neliximab |
| Gene ID | 10312 |
| UniProt | Q13488 |
| Research Area | Immunology |
