| Description | This product is a monoclonal antibody derived from Rat (Rattus norvegicus), which can specifically recognize Triggering Receptor Expressed On Myeloid Cells 2. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation. Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free. |
| Clonality | Monoclonal |
| Host Species | Rat |
| Target Species | Human |
| Immunogen | A peptide comprising amino acids AHVEHSISRS of human TREM2 |
| Isotype | IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and/or SEC-HPLC |
| Endotoxin | <1 EU/mg, determined by LAL method |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C. |
| Application | ELISA; Inhib |
| Application Notes | The antibody is recommended for detection of TREM2 by ELISA, Inhib assays. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | TREM2 |
| Alternative Name | Triggering Receptor Expressed On Myeloid Cells 2; Triggering Receptor Expressed On Myeloid Cells 2a; Triggering Receptor Expressed On Monocytes 2; TREM-2; Trem2a; Trem2b; Trem2c |
| Gene ID | 54209 |
| UniProt | Q9NZC2 |
| Research Area | Signal Pathway |
| Related Disease | Alzheimer's Disease, Frontotemporal Lobar Degeneration, Ftld-Like Syndrome, Parkinson's Disease, Nasu-Hakola Disease, Multiple Sclerosis, Huntington Disease, Immune-Mediated Neuropathies, Amyotrophic Lateral Sclerosis |
