| Description | This human antibody is specific against Varicella zoster virus glycoprotein B (VZV gB). The antibody binds to gB and forms a stable interface with gB Domain IV. It is a human neutralizing antibody which neutralizes VZV and inhibits fusion. This product has been detected using Neutralization assay, Inhibition assay and Immunoprecipitation. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Varicella zoster virus (VZV) |
| Immunogen | Varicella zoster virus |
| Epitope | gB Domain IV |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA; Neut; Inhib; IP |
| Application Notes | This antibody was detected by neutralization assay and Immunoprecipitation (IP). The antibody was performed at 10 μg /mL in Cell-free VZV neutralization assay. For IP, each 20 µg of mAb was incubated with 30 µL protein A beads for 1 h at room temperature on a rotary mixer. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | VZV gB |
| Alternative Name | Varicella zoster virus glycoprotein B |
| Research Area | Infectious Disease |
| Related Disease | Varicella, Zoster |
