Description | This product is a human antibody that recognizes ZIKV Env. The ZIKV-195 monoclonal antibody effectively inhibits a broad range of ZIKV strains, with IC₅₀ values ranging from 77 to 600 ng/mL. |
Clonality | Monoclonal |
Host Species | Human |
Target Species | Zika Virus (ZIKV) |
Cross Reactivity | African strain (Dakar 41525 and MR 766), Asian strain (H/PF/2013 and Malaysian P6740), American strain (Paraiba 2015) |
IC50 | 77-600 ng/mL |
Isotype | Human IgG |
Expression Species | HEK293F or CHO |
Conjugation | None |
Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
Endotoxin | <1 EU/mg |
Purification | Protein A purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
Application | ELISA; Neut |
Application Notes | The mAb effectively inhibits ZIKV strains originating from Africa (Dakar 41525 and MR 766), Asia (H/PF/2013 and Malaysia P6740), and America (Paraiba 2015), with IC₅₀ values ranging from 77-600 ng/mL. |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Flow Cytometry Protocol |
Target | ZIKV Env |
Alternative Name | Zika virus envelope protein; Zika virus; envelope protein; ZIKV; Env; E protein; envelope |
Research Area | Microbiology |