| Description | The product is a novel anti-oligomeric Aβ42 antibody HT7 screened from the human scFv antibody library. The antibody binds to the N-terminal region of oligomeric Aβ42 aggregates. HT7 also attenuates Aβ42 cytotoxicity. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Epitope | N terminal peptide of the Aβ42 molecule |
| Affinity | 3 μM (KD value for scFv HT7 to Aβ42 oligomer) |
| Isotype | Human IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | DB; WB; IHC-P; ELISA; Inhib |
| Application Notes | WB: 1-5 µg/mL IHC-P: 5-10 µg/mL ELISA: 2-10 µg/mL |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | Aβ42 |
| Alternative Name | Beta-amyloid peptide; beta-APP; Amyloid-beta; Aβ; Abeta; Abeta42; APP; Amyloid |
| Research Area | Neuroscience |
