| Description | This is a mouse monoclonal antibody that targets the human AGER protein. The antibody binds to human RAGE with an affinity of 0.236 nM. |
| Clonality | Monoclonal |
| Host Species | Mouse |
| Target Species | Human |
| Affinity | KD = 0.236 nM |
| Isotype | Mouse IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein G affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | ELISA |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | AGER |
| Alternative Name | Advanced Glycosylation End-Product Specific Receptor; RAGE; Receptor For Advanced Glycation End-Products Variant 20; Advanced Glycosylation End Product-Specific Receptor; Receptor For Advanced Glycosylation End Products; Receptor For Advanced Glycation End-Products; RAGE Isoform NtRAGE-Delta; RAGE Isoform SRAGE-Delta; SCARJ1 |
| Gene ID | 177 |
| UniProt | Q15109 |
| Related pathway | MyD88 dependent cascade initiated on endosome and Blood-Brain Barrier and Immune Cell Transmigration |
| Research Area | Immunology |
| Related Disease | RAGE-related disease or disorder; Alzheimer's disease |
