ASTL (N-terminus) Specific Recomb™ Antibody (V3S-0224-CJ15), Mouse IgG2b (CAT#: V3S-0224-CJ15)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description Anti-ASTL antibody (clone SB2) binds to human SAS1B protein, which is coded by ASTL gene. It does not cross-react with mouse SAS1B protein. Recombinant human splice variant A of SAS1B (aa 22-431) was used to generate this antibody. The mAb SB2 does not react with the ECD of SAS1B (aa 164-431) suggesting that its epitope lies in the N-terminus of the protein. The antibody can be used for the inhibition of cells expressing SAS1B.
Clonality Monoclonal
Host Species Mouse
Target Species Human
Immunogen Recombinant human splice variant A of SAS1B (aa 22-431) expressed in E. coli
Epitope N-terminus
Isotype Mouse IgG2b

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and SEC-HPLC
Endotoxin <1 EU/mg
Purification Protein G affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within a week. For longer storage, aliquot and store at -20°C.

Applications

Application ELISA
Application Notes The binding specificity of antibody SB2 to human SAS1B protein was determined by ELISA.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target ASTL
Alternative Name OOMD11; OZEMA11; SAS1B
Gene ID 431705
UniProt Q6HA08
Related pathway 2q11.2 copy number variation syndrome
Research Area Cancer Research
Related Disease Cancer; Oocyte/Zygote/Embryo Maturation Arrest
For research use only, not directly for clinical use.
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