This product is a neutralizing antibody that binds to Crimean-Congo Hemorrhagic Fever virus. ADI-36121 neutralizes CCHFV by blocking Gc homotrimerization in the endosome and preventing membrane fusion. ADI-36121 displays highly potent cross-clade neutralization to CCHFV, which makes it a viable candidate for clinical development.
HEK293F or CHO cell line
Protein A purified
0.2 μM filtered
PBS, pH 7.4
Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.