Description | The antibody is a human IgG4 mAb that binds to human CD274 antigen. In the first evaluation of an immunologic checkpoint inhibitor in healthy HIV-1-infected individuals, it was observed that single low-dose infusions of BMS-936559 appeared to enhance HIV-1-specific immunity in some participants. |
Clonality | Monoclonal |
Host Species | Human |
Target Species | Human |
Isotype | IgG4 |
Expression Species | HEK293F or CHO cell line |
Conjugation | Unconjugated |
Purity | >95% |
Endotoxin | <1 EU/mg |
Form | Liquid |
Purification | Protein A purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
Application | ELISA; Block; FuncS |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Flow Cytometry Protocol |