Recombinant Anti-CD274 Antibody (V3S-0723-FY35) (CAT#: V3S-0723-FY35)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description The antibody is a human IgG4 mAb that binds to human CD274 antigen. In the first evaluation of an immunologic checkpoint inhibitor in healthy HIV-1-infected individuals, it was observed that single low-dose infusions of BMS-936559 appeared to enhance HIV-1-specific immunity in some participants.
Clonality Monoclonal
Host Species Human
Target Species Human
Isotype IgG4

Property

Expression Species HEK293F or CHO cell line
Conjugation Unconjugated
Purity >95%
Endotoxin <1 EU/mg
Form Liquid
Purification Protein A purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Applications

Application ELISA; Block; FuncS

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target CD274
Alternative Name B7-H; B7H1; PDL1; PD-L1; hPD-L1; PDCD1L1; PDCD1LG1; CD274
Gene ID 29126
UniProt Q9NZQ7
Research Area Immunology
For research use only, not directly for clinical use.
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