| Description | This is a mouse monoclonal antibody that specifically targets human CFD. It also demonstrates cross-reactivity with cynomolgus monkey. The antibody exhibits a high IC₅₀ value to CFD, measured at 1.3 nM. |
| Clonality | Monoclonal |
| Host Species | Mouse |
| Target Species | Human, Cynomolgus |
| IC50 | 1.3 nM |
| Isotype | Mouse IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein G affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | ELISA |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | CFD |
| Alternative Name | Complement Factor D; Properdin Factor D; Adipsin; D Component Of Complement (Adipsin); C3 Convertase Activator; EC 3.4.21.46; PFD |
| Gene ID | 1675 |
| UniProt | P00746 |
| Related pathway | Initial triggering of complement and Response to elevated platelet cytosolic Ca2+ |
| Research Area | Signal Pathway |
| Related Disease | Complement Factor D Deficiency and Properdin Deficiency |
