Description | This product is a neutralizing antibody that binds to Cn2 toxin. The antibody recognizes and neutralizes the main toxins from the venoms of the C. noxius and Centruroides suffusus suffususscorpions (Cn2 and Css2, respectively), with affinities in the picomolar range, and removes any poisoning symptoms. In neutralization tests, this clone was capable of inhibiting nearly all symptoms caused by the C. suffusus suffusus venom. |
Clonality | Monoclonal |
Host Species | Human |
Target Species | Centruroides noxius |
Immunogen | Cn2 toxin |
Epitope | N terminus of the α-helical region of the Cn2 toxin |
Isotype | IgG1 |
Expression Species | HEK293F or CHO cell line |
Conjugation | Unconjugated |
Purity | >95% |
Endotoxin | <1 EU/mg |
Form | Liquid |
Purification | Protein A purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
Application | ELISA |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Flow Cytometry Protocol |
Target | Cn2 toxin |
Research Area | Toxin |