| Description | EBI3 is a 34 kDa glycoprotein containing a signal peptide and two fibronectin type III domains, but lacks a membrane anchoring motif; it is secreted and also present on the plasma membrane and endoplasmic reticulum (ER). The Ab7 antibody and Ab7 antibody variants bind to the human EBI3 subunit of IL-27 with high affinity. AB7 is a mouse IgG2a antibody with a wildtype Fc domain. |
| Clonality | Monoclonal |
| Host Species | Mouse |
| Target Species | Human |
| Isotype | IgG2a |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein G purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA; FC |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | EBI3 |
| Alternative Name | IL27B; IL35B; IL-27B; interleukin-27 subunit beta; EBV-induced gene 3 protein; Epstein-Barr virus induced gene 3; IL-27 subunit beta; IL27 subunit; IL35 subunit; cytokine receptor; epstein-Barr virus-induced gene 3 protein |
| Gene ID | 10148 |
| UniProt | Q14213 |
| Research Area | Immunology; Cancer Research |
