| Description | This is a mouse antibody product that specifically targets F. hepatica cathepsin L1. Cathepsin L1 is a significant part of the excretory/secretory material in adult parasites and is an essential candidate for a vaccine. This marks the initial documentation of creating a phage display antibody library from an F. hepatica infected host. Furthermore, it is also the first time such a library has been utilized to discover an affinity-matured monoclonal antibody fragment that binds to an F. hepatica antigen. |
| Clonality | Monoclonal |
| Host Species | Mouse |
| Target Species | Fasciola hepatica |
| Isotype | Mouse IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein G purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | ELISA |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | F. hepatica cathepsin L1 |
| Alternative Name | Fasciola hepatica cathepsin L1; Fasciola hepatica; cathepsin L1; Fasciola hepatica; FhCatL1 |
| Research Area | Immunology |