| Description | This product is a human antibody that specifically targets the GII.4 P domain of human norovirus. This antibody recognizes a region of P2002 that is largely conserved in the GI and GII genomes. It is a non-blocking antibody which binds to a highly conserved epitope within the P domain. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Norovirus (NV) |
| Cross Reactivity | GI.1, GI.3, GI.4, GII.1, GII.2, GII.3, GII.4c, GII.14, GII.17 |
| Epitope | P domain |
| Isotype | Human IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | ELISA |
| Application Notes | The ELISA method was used to determine the binding specificity of the antibody to various GI and GII genotype VLPs. This antibody recognizes GI.1, GI.3, GI.4, GII.1, GII.2, GII.3, GII.4c, GII.14, GII.17 in ELISA. This antibody does not neutralize norovirus. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | HuNoVs GII.4 |
| Alternative Name | GII.4 2002 norovirus; P domain; norovirus; VLP; P2002; Human norovirus; HuNoV |
| Research Area | Microbiology |
