| Description | Human IL4 can be specifically recognized by clone CODV, which is a recombinant human IgG antibody that can be used for ELISA detection. CODV proteins are fully functional in antigen binding. The reference also showed potent inhibition of cell signaling proteins by inhibiting IL4, IL13 or TNF signaling in cellular assays: IC50 values for IL4, IL13 or TNF signaling ranged from 33 to 54 pM, 0.9 to 4.5 nM and 95 to 785 nM, respectively. Therefore, CODV-Igs have the potential to meet therapeutic goals for clinical application. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Isotype | IgG |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA; FuncS |
| Application Notes | Cellular assays: IC50 values of this antibody for IL4, IL13 or TNF signaling ranged from 33 to 54 pM, 0.9 to 4.5 nM and 95 to 785 nM. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
