| Description | The 3D6-2F4 antibody has exhibited a significant binding affinity to CHO-S cells expressing the human DEC-205 protein. This antibody was developed through the immunization of the HC2/KCo7 strain of HuMAb transgenic mice with a soluble form of the human DEC-205 antigen. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Immunogen | A soluble fusion protein comprising a DEC-205 extracellular domain (comprising all ten lectin-binding domains) fused with an antibody Fc domain. |
| Epitope | Extracellular domain of human DEC-205 |
| Affinity | KD = 80 pM |
| Isotype | Human IgG1 |
| Expression Species | HEK293F or CHO |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | FC; ELISA; IF |
| Application Notes | ELISA: 10 μg/mL |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | LY75 |
| Alternative Name | DEC-205; CD205 protein |
| UniProt | Q6WY07 |
| Related pathway | Wnt/β-catenin signaling pathway |
| Research Area | Cancer Research; Signal Pathway |
| Related Disease | Infectious disease |
