Description | This is a human antibody that targets human MPIG6B. The G6b-B receptor, which contains the immunoreceptor tyrosine-based inhibition motif (ITIM), plays a crucial role in platelet production and activation. Deficiency of G6b-B leads to significant macrothrombocytopenia, myelofibrosis, and abnormal platelet function in both mice and human. |
Clonality | Monoclonal |
Host Species | Human |
Target Species | Human |
Isotype | Human IgG |
Expression Species | HEK293F or CHO |
Conjugation | None |
Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
Endotoxin | <1 EU/mg |
Purification | Protein A purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
Application | ELISA |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Flow Cytometry Protocol |