N. meningitidis fHbp variant 3 Specific Recomb™ Antibody (V3S-1023-FY103), Human IgG (CAT#: V3S-1023-FY103)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description This product is a human antibody that recognizes neisseria meningitidis fHbp variant 3. This antibody binds to fHbp variant 3 of Neisseria meningitidis. It is able to elicit complement-mediated bactericidal activity in rabbits, but not human, against fHbp-displaying meningococci from any of 3 different variant groups.
Clonality Monoclonal
Host Species Human
Target Species Neisseria meningitidis
Affinity KD = 0.265 nM (fHbp v1)
KD = 0.036 nM (fHbp v2)
KD = 2.7 nM (fHbp v3)
Isotype Human IgG

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and SEC-HPLC
Endotoxin <1 EU/mg
Purification Protein A purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within a week. For longer storage, aliquot and store at -20°C.

Applications

Application ELISA; FC; SPR
Application Notes SPR: 10 ug/mL

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target N. meningitidis fHbp variant 3
Alternative Name Neisseria meningitidis fHbp variant 3; Neisseria meningitidis; fHbp variant 3; Neisseria meningitidis factor H binding protein; factor H binding protein; fHbp v3
Research Area Microbiology
For research use only, not directly for clinical use.
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