| Description | This product is a mouse monoclonal antibody that recognizes human QSOX1 and can be used in ELISA, FC, IF. MAb492.1 inhibits HsQSOX1 but not MmQSOX1. MAb492.1 efficiently inhibited HsQSOX1 activity, and consequently inhibited adhesion and migration of cancer cells to and through fibroblasts from corresponding tissues. |
| Clonality | Monoclonal |
| Host Species | Mouse |
| Target Species | Human |
| Immunogen | Recombinant human QSOX1 (HsQSOX1) |
| Epitope | The N-terminal QSOX1 Trx domain |
| Neutralization Mechanism | The antibody blocks substrate access to the Trx CXXC redox-active site of human QSOX1. |
| Affinity | Ki=0.9 ± 0.1 nM |
| Isotype | Mouse IgG1 |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein G purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservative |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | ELISA; FC; IF |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
