Recombinant Anti-RHOA/RHOB/RHOC Antibody (V3S-0723-FY183) (CAT#: V3S-0723-FY183)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description The mAb is an antibody that exhibits selective binding to the GTP-bound form of RhoA, RhoB, and RhoC. The characterization of the mAb reveals its function as a conformational sensor specifically targeting the activated forms of RhoA, RhoB, and RhoC. However, it should be noted that the antibody demonstrates a relatively low affinity for these targets, with a Kd value of 3 µM.
Clonality Monoclonal
Host Species Human
Target Species Human
Immunogen Recombinant GST-fused Rho protein
Affinity 3 µM
Isotype IgG

Property

Expression Species HEK293F or CHO cell line
Conjugation Unconjugated
Purity >95%
Endotoxin <1 EU/mg
Form Liquid
Purification Protein A purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Applications

Application ELISA; WB

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target RHOA/RHOB/RHOC
Alternative Name ARHA; ARH12; RHO12; EDFAOB; RHOH12; RHOA
Gene ID 387
UniProt P61586
Research Area Signal Pathway
For research use only, not directly for clinical use.
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