| Description | This antibody specifically binds to the Kunitz domain 1 and the Kunitz domain 2 of human TFPI (tissue factor pathway inhibitor). It can block TFPI and activate an extrinsic pathway of blood coagulation. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human, Mouse |
| Epitope | Kunitz domain 1 and the Kunitz domain 2 |
| EC50 | 0.09 nM (human TFPI); 0.06 nM (mouse TFPI) |
| Isotype | Human IgG1 |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | ELISA; Inhib |
| Application Notes | The binding affinity of this antibody was measured by ELISA. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Post Translational Modification | O-glycosylated. |
