| Description | This antibody (clone MEH63) is against Methicillin-resistant S. aureus (MRSA) cells through the S. aureus TrkH family potassium uptake protein. The TrkH family potassium uptake protein recognised by MEH63 is the potassium-conducting subunit of the Trk transport system, involved in the vitality of bacteria. MEH63 exhibited the high reduction in the viability of S. aureus S.a.48 (~44%y) and S. aureus S.a.61 (~52%). |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Methicillin-resistant S. aureus (MRSA) |
| Cross Reactivity | S. epidermidis, S. pyogenes |
| Neutralization Mechanism | Inhibit the viability of S. aureus |
| Function | The TrkH family potassium uptake protein is the potassium-conducting subunit of the Trk transport system, involved in the vitality of bacteria. |
| Isotype | Human IgG |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | WB; Inhib |
| Application Notes | The binding of MEH63 to MRSA TrkH family potassium uptake protein was confirmed by Western blotting. MEH63 exhibited strong binding to S. aureus S.a.124 and moderate binding to S. epidermidis (strain 12228) and S. pyogenes (strain 10403). |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | TrkH family potassium uptake protein |
| Alternative Name | TrkH |
| Research Area | Microbiology |
| Related Disease | MRSA bacteraemia |
