Acanthamoeba castellani and other species is an emerging cause of corneal infections, causing severe pain and visual impairment and forming a characteristic lesion. Myosin II heavy chain is two-headed. It self-assembles into filaments. Hexamer of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2).