AIMP1 (Aminoacyl tRNA synthetase complex interacting multifunctional protein 1) is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. AIMP1 is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells.