Adhesion molecule interacting with CXADR antigen 1
JAML (Junction Adhesion Molecule Like) is a Protein Coding gene. Among its related pathways are Cell surface interactions at the vascular wall and Class I MHC mediated antigen processing and presentation. An important paralog of this gene is SCN2B. AMICA1 may function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells.