Apolipoprotein B

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This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.
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Anti-APOB Neutralizing Antibody (V3S-0622-YC829) (CAT#: V3S-0622-YC829)

Target: APOB

Host Species: Human

Target Species: Human,

Application: FuncS,

Inquiry

Anti-APOB Neutralizing Antibody (V3S-0622-YC830) (CAT#: V3S-0622-YC830)

Target: APOB

Host Species: Human

Target Species: Human,

Application: FuncS,

Inquiry

Anti-APOB Neutralizing Antibody (V3S-0622-YC831) (CAT#: V3S-0622-YC831)

Target: APOB

Host Species: Human

Target Species: Human,

Application: FuncS,

Inquiry

Anti-APOB Neutralizing Antibody (V3S-0622-YC832) (CAT#: V3S-0622-YC832)

Target: APOB

Host Species: Human

Target Species: Human,

Application: FuncS,

Inquiry

Anti-APOB Neutralizing Antibody (V3S-0622-YC833) (CAT#: V3S-0622-YC833)

Target: APOB

Host Species: Human

Target Species: Human,

Application: FuncS,

Inquiry

Anti-APOB Neutralizing Antibody (V3S-0622-YC834) (CAT#: V3S-0622-YC834)

Target: APOB

Host Species: Human

Target Species: Human,

Application: FuncS,

Inquiry

Anti-APOB Neutralizing Antibody (V3S-0622-YC835) (CAT#: V3S-0622-YC835)

Target: APOB

Host Species: Human

Target Species: Human,

Application: FuncS,

Inquiry

Anti-APOB Neutralizing Antibody (V3S-0622-YC836) (CAT#: V3S-0622-YC836)

Target: APOB

Host Species: Human

Target Species: Human,

Application: FuncS,

Inquiry

Anti-APOB Neutralizing Antibody (V3S-0622-YC837) (CAT#: V3S-0622-YC837)

Target: APOB

Host Species: Human

Target Species: Human,

Application: FuncS,

Inquiry

Anti-APOB Neutralizing Antibody (V3S-0622-YC838) (CAT#: V3S-0622-YC838)

Target: APOB

Host Species: Human

Target Species: Human,

Application: FuncS,

Inquiry

Anti-APOB Neutralizing Antibody (V3S-0622-YC839) (CAT#: V3S-0622-YC839)

Target: APOB

Host Species: Human

Target Species: Human,

Application: FuncS,

Inquiry

Recombinant Anti-APOB Antibody (V3S-0522-YC13) (CAT#: V3S-0522-YC13)

Target: APOB

Host Species: Mouse

Target Species: Human,

Application: ELISA,

Inquiry

Recombinant Anti-APOB Antibody (V3S-0522-YC14) (CAT#: V3S-0522-YC14)

Target: APOB

Host Species: Mouse

Target Species: Human,

Application: ELISA,

For research use only, not directly for clinical use.


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