Bestrophin 1

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Bestrophin 1 belongs to the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies.
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Recombinant Anti-BEST1 Antibody (V3S-0522-YC742) (CAT#: V3S-0522-YC742)

Target: BEST1

Host Species: Mouse

Target Species: Chicken,

Application: ELISA,

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Recombinant Anti-BEST1 Antibody (V3S-0522-YC7628) (CAT#: V3S-0522-YC7628)

Target: BEST1

Host Species: Human

Target Species: Chicken,

Application: WB,ELISA,FuncS,

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Clone MO67734, Anti-Chicken BEST1 Monoclonal Antibody (CAT#: F25103)

Target: BEST1

Host Species: Mouse

Target Species: Chicken,

Application: WB,Neut,FuncS,

For research use only, not directly for clinical use.


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