bone morphogenetic protein 5

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Bmp5 is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Mice with null mutations in this gene exhibit a short ear phenotype, which is characterized by reduced size of the external ear, altered size and shape of the sternum, and other skeletal and soft-tissue abnormalities.
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Anti-Bmp5 Neutralizing Antibody (V3S-0822-YC420) (CAT#: V3S-0822-YC420)

Target: Bmp5

Host Species: Rat

Target Species: Mouse,

Application: Neut,

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Anti-BMP5 Neutralizing Antibody (V3S-0822-YC419) (CAT#: V3S-0822-YC419)

Target: BMP5

Host Species: Mouse

Target Species: Human,

Application: Neut,

For research use only, not directly for clinical use.


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