Bermuda grass (Cynodon dactylon; subfamily Chloridoideae) is an important source of seasonal aeroallergens in warm tropical and sub-tropical areas worldwide. Cyn d 1, the major allergen of BGP, is the most abundant protein component of BGP, comprising 15-20% of crude pollen extract. It dominates the human IgE response with 87% of individuals allergic to BGP showing positive reaction to this 32 kDa protein. Clinical evidence of cross-reactivity among grass pollens has suggested that diagnosis and effective immunotherapy can be achieved with a limited number of grasses, although the selection of species to treat against is based on regional prevalence and taxonomic relationship. Grass group 1 allergens, with molecular weights in the range of 31-35 kDa, are recognized as one of the most prominent allergenic components of pollen extracts.