CεmX

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Membrane-bound IgE (mIgE) is part of the IgE-BCR and is essential for generating isotype-specific IgE responses. On mIgE+ B cells, the membrane-bound ε-chain (mε) exists predominantly in the long isoform, mεL, containing an extra 52 aa CεmX domain between CH4 and the C-terminal membrane-anchoring segment; the short isoform of mε, mεS, exists in minor proportions. CεmX thus provides an attractive site for immunologic targeting of mIgE+ B cells.

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Recombinant Anti-CεmX Antibody (V3S-1022-YC2881) (CAT#: V3S-1022-YC2881)

Target: CεmX

Host Species: Human

Target Species: Human,

Application: WB,ELISA,FC,Apop,Cyt,