Complement 1q

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The C1q complex is a protein complex. It is part of the complement system. It is potentially multivalent for attachment to the complement fixation sites of immunoglobulin. The sites are on the CH2 domain of IgG and, it is thought, on the CH4 domain of IgM. The appropriate peptide sequence of the complement fixing site might become exposed following complexing of the immunoglobulin, or the sites might always be available, but might require multiple attachment by C1q with critical geometry in order to achieve the necessary avidity.

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Anti-C1Q Neutralizing Antibody (V3S-0622-YC1130) (CAT#: V3S-0622-YC1130)

Target: C1Q

Host Species: Mouse

Target Species: Human,

Application: FuncS,