C-type lectin domain containing 6A

Product list
CLEC6A is a type II membrane receptor with an extracellular C-type lectin-like domain fold. The extracellular portion binds structures with a high mannose content and has been shown to recognize several pathogens, including C. elegans, S. cerevisiae, M. tuberculosis, C. neoformans, and house dust mite. When stimulated, the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway, leading to the induction of cytokines. Two transcript variants encoding different isoforms have been found for this gene.
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Anti-CLEC6A Neutralizing Antibody (V3S-0822-YC839) (CAT#: V3S-0822-YC839)

Target: CLEC6A

Host Species: Mouse

Target Species: Human,

Application: FC,Neut,

For research use only, not directly for clinical use.

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