Fc fragment of IgA receptor

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FCAR is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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Anti-FCAR Neutralizing Antibody (V3S-0622-YC1579) (CAT#: V3S-0622-YC1579)

Target: FCAR

Host Species: Human

Target Species: Human,

Application: ELISA,FC,Inhib,IP,