Hypoxia Inducible Factor 1 Alpha Subunit

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This protein is the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease.

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Anti-HIF1A Neutralizing Antibody (V3S-0622-YC1701) (CAT#: V3S-0622-YC1701)

Target: HIF1A

Host Species: Mouse

Target Species: Human,

Application: WB,Inhib,