major histocompatibility complex, class I, E

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HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.
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Anti-HLA-E Neutralizing Antibody (V3S-0822-YC1275) (CAT#: V3S-0822-YC1275)

Target: HLA-E

Host Species: Mouse

Target Species: Avian, Chicken, Turkey,

Application: Neut,WB,FC,IHC,IHC-Fr,IP,

For research use only, not directly for clinical use.

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