major histocompatibility complex, class I, G

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HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.

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Recombinant Anti-HLA-G (a3 domain) Antibody (V3S-0522-YC2266) (CAT#: V3S-0522-YC2266)

Target: HLA-G

Host Species: Mouse

Target Species: Human,

Application: ELISA,