Laminin-5 alpha3 chain LG4/5 domain

Product list

This protein belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This protein is an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome.

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Recombinant Anti-LG4/5 Antibody (V3S-0622-YC2037) (CAT#: V3S-0622-YC2037)

Target: LG4/5

Host Species: Mouse

Target Species: Human,

Application: ELISA,