Methoxy tryptase (Matriptase) is a protein which first checks in a mouse thymic epithelial cells. Methoxy tryptase (Matriptase) is isolated from the human cell carcinoma cell was named as methoxy tryptase (Matriptase), MT-SP1 or ST14 and the like. Tome tryptase (Matriptase) has been its expression is markedly increased in most epithelial-derived cancer cells, including ovarian cancer, prostate cancer, cervical cancer, breast cancer, also became known in recent years for expression in macrophages. Methoxy tryptase (Matriptase) is a functionally type II membrane protease (type II transmembrane serine protease), is known to be involved in the normal epithelial cell differentiation and cancer.