MHC Class I Polypeptide-Related Sequence A and MHC Class I Polypeptide-Related Sequence B

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MIC (e.g., MICA, MICB) is a ligand for NKG2D, a receptor that is expressed on most human NK cells, γδ T cells, and CD8+ T cells. While NKG2D ligands are not usually found on healthy tissues, various forms of cellular stress, including DNA damage, upregulate ligand expression, resulting in their frequent detection in multiple solid and hematologic malignancies,including melanoma.

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Recombinant Anti-MICA / MICB Antibody (V3S-0522-YC721) (CAT#: V3S-0522-YC721)

Target: MICA / MICB

Host Species: Mouse

Target Species: Human,

Application: WB,DB,ELISA,