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Are you currently facing challenges in vaccine development, serotyping, or rapid diagnostic assay creation for Neisseria meningitidis? Creative Biolabs' N. meningitidis Specific Antibody Products help you overcome these hurdles by providing the precision and reliability required for robust research and diagnostic applications. Through advanced protein engineering and high-throughput screening platforms, our solutions enable you to accurately detect and characterize this critical pathogen, streamlining your workflow and accelerating your project's success.
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Neisseria meningitidis is a Gram-negative bacterium causing severe invasive diseases like meningitis and septicemia. A major cause of bacterial meningitis, it is characterized by a polysaccharide capsule that forms the basis for serogroup classification. The most common serogroups causing invasive disease are A, B, C, W, Y, and X. A commensal of the human nasopharynx, it can invade the bloodstream and central nervous system in susceptible individuals. The bacterium's pathogenesis involves surface components like pili and outer membrane proteins. Understanding these antigens is key to developing diagnostics and vaccines.
Fig.1 Scanning electron micrograph of a single N. meningitidis cell.Distributed under CC BY-SA 4.0, from Wiki, without modification
Antibodies targeting N. meningitidis are essential tools for research and clinical applications. They recognize components like the capsular polysaccharide and outer membrane proteins, enabling accurate detection and characterization. A significant application is in serogroup-specific diagnostic assays, which help determine the infecting strain's serogroup to guide treatment. Published data highlights the use of anti-capsular polysaccharide antibodies in diagnostics, vaccine development, and quality control, ensuring consistent expression of target antigens.
Creative Biolabs leads in high-quality, specific antibody products, with a commitment to providing researchers and diagnostic developers with the most reliable tools.
Key advantages of partnering with Creative Biolabs:
A: These antibodies are highly versatile and validated for a wide range of applications, including ELISA, Western Blotting, Immunohistochemistry, and flow cytometry. They are designed to meet the stringent requirements of both basic scientific research into bacterial pathogenesis and the development of clinical diagnostic assays for infectious diseases.
A: Our antibodies undergo rigorous purification and validation, including extensive cross-reactivity testing against other bacterial strains and related antigens. We use advanced immunoassay techniques to confirm their precise binding to N. meningitidis antigens, minimizing off-target interactions and ensuring the high specificity and sensitivity crucial for accurate research and diagnostic outcomes.
A: Antibody-based immunoassays provide a significant advantage in speed and sensitivity. Unlike culture methods, which can take days to yield results, immunoassays can provide rapid results, often within hours. This is critical for early diagnosis of a fast-progressing disease like meningococcal disease. Additionally, they can detect bacterial antigens even in samples where the organism is no longer viable, which is a major limitation for culture-based methods.
A: Yes, our antibody product line includes specific antibodies developed to recognize the capsular polysaccharides of the major disease-causing serogroups (e.g., A, B, C, Y, W). This enables precise serogrouping and is a vital tool for epidemiological surveillance and public health management.
Creative Biolabs' N. meningitidis Specific Antibody Products provide the scientific community with a powerful suite of tools for addressing the challenges of meningococcal disease research and diagnostics. Our commitment to scientific excellence, combined with our advanced engineering and rigorous quality control, ensures that our antibodies deliver unparalleled specificity, sensitivity, and reliability. From serotyping and vaccine development to fundamental research into bacterial pathogenesis, our products empower you to achieve accurate, reproducible, and impactful results.
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Recombinant Anti-N. meningitidis Antibody (V3S-0522-YC7516) (CAT#: V3S-0522-YC7516)
Target: N. meningitidis
Host Species: Mouse
Target Species: Neisseria meningitidis,
Application: WB,IHC,FuncS,