nuclear receptor subfamily 3 group C member 2

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NR3C2 is the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy.
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Anti-NR3C2 Neutralizing Antibody (V3S-0822-YC2154) (CAT#: V3S-0822-YC2154)

Target: NR3C2

Host Species: Mouse

Target Species: Human, Mouse, Rat, Chicken, Rabbit, Sheep,

Application: WB,Neut,FC,ICC,IF,IHC,IHC-P,

For research use only, not directly for clinical use.

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