Prostaglandin E receptor 4 (subtype EP4)

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Prostaglandin E receptor 4 (subtype EP4) belongs to the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses.

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Recombinant Anti-PTGER4 Antibody (V3S-0522-YC5927) (CAT#: V3S-0522-YC5927)

Target: PTGER4

Host Species: Mouse

Target Species: Human,

Application: FC,