Roundabout Guidance Receptor 1

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Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of This is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene.

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Anti-ROBO1 Neutralizing Antibody (V3S-0622-YC2518) (CAT#: V3S-0622-YC2518)

Target: ROBO1

Host Species: Mouse

Target Species: Human,

Application: FuncS,