Serratia marcescens Specific Neutra™ Antibody Products
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Are you currently facing challenges in rapid and specific bacterial identification within complex clinical or environmental samples, or struggling to develop reliable serological assays for infection monitoring? Our S. marcescens Specific Neutra™ Antibody Products help you achieve rapid, precise, and reliable detection and quantification of this critical opportunistic pathogen, enabling robust diagnostic development and fundamental research through advanced high-specificity Neutra™ Antibody Products.
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Introduction of S. marcescens
Serratia marcescens (S. marcescens) is a ubiquitous, Gram-negative, facultative anaerobic bacillus belonging to the Enterobacteriaceae family. It is a critical opportunistic pathogen, widely found in environmental and hospital settings. A key characteristic is the production of the red-to-pink pigment prodigiosin, which is researched for its potential antimicrobial properties. In clinical settings, S. marcescens is a major cause of nosocomial (hospital-acquired) infections, including UTIs, pneumonia, and septicemia. Its success is driven by virulence factors like adhesins, motility, and the secretion of enzymes (e.g., proteases), coupled with a high propensity for multi-drug resistance. Due to the high potential for severe infections, accurate and specific detection tools are crucial for effective epidemiological and clinical management.
Fig.1 Mechanisms of antibiotic resistance in S. marcescens.1
Antibodies Against S. marcescens
Antibodies specifically targeting S. marcescens are foundational reagents for rapidly and unequivocally identifying the pathogen, distinguishing it from other colonizing flora, and investigating its molecular mechanisms. Creative Biolabs' S. marcescens Specific Neutra™ Antibodies are designed to bind with high specificity to key surface components or whole-cell antigens, ensuring reliable detection.
Versatile Applications of S. marcescens Antibodies:
| Application Type | Scientific Utility | Example Technique |
| Bacterial Identification | Rapidly confirm the presence of S. marcescens in clinical or environmental specimens. | Enzyme-Linked Immunosorbent Assay (ELISA) |
| Pathogen Localization | Visualize the distribution and concentration of the bacteria within biofilms or host tissues. | Immunofluorescence (IF), Immunocytochemistry (ICC) |
| High-Throughput Screening | Quantify bacterial load for drug efficacy studies or monitor contamination levels in water systems. | Flow Cytometry, High-Content Screening (HCS) |
| Serological Research | Characterize the specific antigens expressed by different strains of S. marcescens. | Western Blotting |
These applications allow researchers and diagnostic developers to move beyond traditional, time-consuming culture methods, providing the precision necessary to address the complex challenges posed by multi-drug resistant strains of this pathogen.
Why Choose Us?
At Creative Biolabs, we provide the critical reagents to accelerate your research into microbial pathogenesis and diagnostic development, backed by over 20 years of specialist experience for peak product performance.
Key Advantages of Creative Biolabs' Neutra™ Antibody Products:
- Unparalleled Specificity: Rigorously screened to ensure minimal cross-reactivity with other bacteria, maximizing assay accuracy.
- Robust Performance: Validated for optimal functionality across formats, including ELISA, IF, and Flow Cytometry.
- High Consistency: Stringent QC guarantees reliable, reproducible results across large manufacturing batches.
- Expertise-Driven Targets: Our years of experience ensures antibody development targets the most scientifically relevant S. marcescens antigens.
- Proven Success: Successfully used in diverse settings for rapid pathogen identification.
FAQs
Q: What is the primary advantage of using specific antibodies over culture?
A: Specific antibodies offer drastically reduced identification time (minutes/hours vs. days for culture), which is essential for rapid clinical decisions, infection control, and high-throughput screening.
Q: How do I select the right antibody target?
A: Choose antibodies validated against key, constitutively expressed surface antigens or virulence proteins. Review data confirming specificity and cross-reactivity profiles, and consult with an expert to align the target with your scientific or diagnostic goals.
Q: Are these antibodies compatible with both rapid tests and quantitative methods?
A: Yes. Their high affinity and stability make them suitable for both qualitative, rapid membrane-based assays (like lateral flow) and robust, quantitative, plate-based methods (like ELISA).
Q: What is the key consideration for accurate sample preparation from complex matrices?
A: Effective sample preparation is critical. You must optimize extraction (e.g., lysis, filtration, dilution) to ensure the target antigen is accessible while minimizing matrix interference. Validation is key to maximizing antigen yield without compromising binding.
Q: Are custom antibodies available for unique S. marcescens strains?
A: Yes. If your project requires an antibody with affinity for a novel or strain-specific epitope, we offer specialized custom development to perfectly match your unique research requirements.
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REFERENCES
- Tavares-Carreon, Faviola et al. "Serratia marcescens antibiotic resistance mechanisms of an opportunistic pathogen: a literature review." PeerJ vol. 11 e14399. 5 Jan. 2023, Distributed under Open Access license CC BY 4.0, without modification. https://doi.org/10.7717/peerj.14399
